|
KMID : 1188320130070020239
|
|
Gut and Liver
2013 Volume.7 No. 2 p.239 ~ p.245
|
|
|
Endoscopic Papillectomy for Benign Ampullary Neoplasms: How Can Treatment Outcome Be Predicted?
|
|
Ahn Dong-Won
Ryu Ji-Kon
Kim Jai-Hwan
Yoon Won-Jae
Lee Sang-Hyub
Kim Yong-Tae
Yoon Yong-Bum
|
|
|
Abstract
|
|
|
Background/Aims:Endoscopic papillectomy is increasingly performed with curative intent for benign papillary tumors. This study was performed to identify factors that predict the presence of malignancy and affect endoscopic success.
Methods:We retrospectively analyzed the medical records of patients who received an endoscopic papillectomy for papillary adenoma from 2006 to 2009.
Results:A total of 43 patients received endoscopic papillectomy. The pathologic results after papillectomy revealed adenocarcinoma in five patients (12%), and the risk of malignancy was high in cases of large lesions, preprocedural pathology of high-grade dysplasia or high serum alkaline phosphatase. Endoscopic success was observed in 37 patients (86%) at the end of follow-up (mean duration, 10.4±9.6 months). The factor significantly affecting success was a complete resection at the initial papillectomy (p=0.007). Two patients experienced recurrence 10 and 32 months after the complete resection, but both achieved endoscopic success with repeated endoscopic treatment. Six patients with endoscopic failure received surgical resection.
Conclusions:Endoscopic papillectomy is a safe and effective method for the curative resection of benign papillary tumors, especially when complete resection is achieved at the initial papillectomy. Follow-up with surveillance should be performed for at least 3 years because of the possible recurrence of tumors during these periods.
|
|
|
KEYWORD
|
|
|
Endoscopic sphincterotomy, Benign papillary tumor, Adenocarcinoma, Endoscopic success
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|